How Much Does a Full STD Panel Cost? The 2026 Price Guide

"Full STD panel" has no fixed definition and no fixed price — which is exactly why a cost guide has to work from published numbers, itemized panels, and the add-ons services sell at checkout. Here is the category's pricing at the time of writing, drawn from the services' own published pages. Two framing notes before the numbers: prices change (the live figure is always at checkout), and cost is only one input — whether and when to screen, and for what, is a healthcare-provider conversation informed by CDC screening guidance, not a budgeting exercise. Screening is not diagnosis.

The headline numbers

So the honest range for a multi-infection panel is $139–$409 as published, with the price driven less by quality than by model (lab-visit vs. mail-in — compared here) and by infection count. Per infection covered, the published math at the flagship tier: STDCheck ~$14/infection, Everlywell ~$28, myLAB Box ~$26–29.

Individual tests, if you don't need a panel

Panels are bundles; the a-la-carte menu is often the cheaper answer when you and your provider have a specific test in mind. STDCheck publishes individual tests from $24 (hepatitis A, B, or C) through $45–59 (herpes types, chlamydia, gonorrhea, syphilis at $49) up to $129 for HIV RNA early detection. Personalabs runs a direct-order menu where STD tests sit alongside 400+ general labs, published from around $49 per test — the consolidation play if you want broader blood work in the same order. What each test actually looks for is explained without marketing at MedlinePlus: chlamydia, gonorrhea, syphilis, HIV screening, hepatitis, herpes.

The add-ons that move the total

Early-detection upgrades. STDCheck publishes HIV RNA early detection at $129 standalone or +$119 added to a panel — the single biggest line-item in the category. Whether an early-detection test fits your timing is precisely a window-period question for a clinician (CDC's HIV testing pages cover the public guidance).

Retesting. Budget for the pattern, not the purchase: window-period follow-ups and post-treatment retesting (described in CDC guidance for some infections) mean one panel is often not the whole spend. Our piece on testing timing covers why.

Shipping and logistics. Mail-in kits price shipping in (myLAB Box states free shipping over $150); lab-visit services have none. Rejected self-collected samples can add a redo cycle — not a fee, but a delay.

Consults. The services above state that consultations on certain positive results are included; confirm in the published policy rather than assuming.

Ways to pay, honestly ranked

Cash-pay DTC (everything above) creates no insurance claim — the privacy trade covered in our cash-pay guide. HSA/FSA cards are commonly accepted and can make the same sticker price cheaper in after-tax terms — with the honest caveat that card acceptance is not plan coverage (the HSA/FSA guide walks the IRS rules). Insurance-billed testing through your own provider can beat every number here if your plan covers screening — the trade is the claim record and possibly explanation-of-benefits mail. And the option price guides underweight: free and low-cost community testing exists — the CDC's Getting Tested pages point to it directly. A price guide that never says "you might legitimately pay $0" is a sales page.

One state note: New York, New Jersey, and Rhode Island regulate direct-to-consumer lab ordering differently than most states — confirm availability in a service's own FAQ before planning around a price.

What drives price that isn't quality

All of the services here run samples through the same federal certification class — CLIA-certified laboratories, the program CMS administers. Paying $409 instead of $139 does not buy a better laboratory; it buys a different model (home collection), a longer infection list, or both. That is the central consumer insight of the category: compare panels on contents and model, not on price-implies-quality.

The bottom line

A focused lab-visit panel runs $139 published (STDCheck — our full review); never-leave-home mail-in panels run $169–$409 published; single tests run $24–$129; and $0 community options exist and are pointed to by the CDC itself. Decide the screening question with a provider first, then buy the cheapest version of the thing you actually decided on — the full field comparison and our services table hold the live numbers.

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This article is for informational purposes only. This is not medical advice — consult a healthcare provider about testing decisions and what results mean for you. Some links on this page are affiliate links; we may earn a commission at no extra cost to you, and it never changes a comparison. LabScored is an independent publisher, not a healthcare provider or laboratory.